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Discussion Question: Hypersensitivity

By the due date assigned, respond to the case study questions below and submit your responses to the Discussion Area.

Respond to the question using the lessons and vocabulary found in the readings. Support your answers with examples and research. Your responses should clarify your understanding of the topic. They should be your own, original, and free from plagiarism. Follow APA format for writing style, spelling and grammar, and citation of sources.

Start reviewing and responding to the postings of your classmates as early in the week as possible. Respond to at least two of your classmates. Participate in the discussion by analyzing each response for completeness and accuracy and by suggesting specific additions or clarifications for improving the discussion question response. Complete your participation for this assignment by the end of the week.

Case Study:

A 19 month old infant presents with marked leg swelling, pain, and irritability to walk within 6 hours of receiving booster vaccinations.

Past medical history:
Primary immunizations received at 6, 10, and 14 weeks of age consisting of trivalent oral polio vaccine administered by mouth, hepatitis B virus vaccine, Haemophilus vaccine and diphtheria, pertussis and tetanus vaccine. No other childhood illnesses.

Allergies:
No prior adverse reactions noted

Physical Exam:
Vitals 38.5 degree Celsius
Respiratory rate, blood pressure and Heart Rate: normal for age
Musculoskeletal: marked swelling of the right thigh with tenderness; no discernable edema of the left thigh and no generalized edema
Skin: erythema of right thigh

Question answers should be based on evidence found in readings and from peer-reviewed literature. At least two sources must be used and cited in APA format for each question. Only one source can be a textbook. Resources should generally be within 5 years unless you are explaining the pathophysiology of a disease or providing pertinent background information

Discussion Questions:

1. Review the types of hypersensitivity reactions, describe what type of hypersensitivity reaction is involved in this case, and support with evidence.
2. According to national guidelines, what would you advise parents regarding further immunization practices?
3. Describe the pathophysiological basis for this type of hypersensitivity reaction.